Nutrition and Brain Health

Exploring the role and effects of diet and food components on brain health

Task Force Information

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members

Contact Information

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specific questions

Activity Overview

Overview of ongoing and
upcoming activities

Expert Groups

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Publications

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Task Force

Multimedia

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Completed Expert Groups

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each activity

Task Force Information

Objectives

This Task Force brings the focus on the role of nutrition and diet for optimising brain development and maintaining brain health across lifespan. To do so, the Task Force drives scientific knowledge on the effects of food components on brain developments and maintenance of brain functions. It also reviews the latest scientific evidence to make it available to a wider scientific community; and increases awareness of the importance of nutrition for the maintenance of brain health across the lifespan.

Task Force Members


*Scientific Advisor

Contact Information

For more detailed information, please contact Isabelle Guelinckx at iguelinckx@ilsieurope.be

Activity Overview

Given the success of our previous "Nutrition for the Ageing Brain" symposia, we are already planning the organisation the 5th edition in 2024. One of the key successes was to have a tripartite organising committee that was able to identify key topics of interest for all interested stakeholders. If you wish to co-create the next edition this unique event, sign up for this task force.

Expert Groups

Coming soon

Publications

All Publications

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Nutrition and Brain Health

NUTRITION, DEVELOPMENT& HEALTHY AGEING

The EAT-Lancet Commission devised a sustainable reference diet with the aim of reducing the incidence of non-communicable diseases and mortality globally while improving food system sustainability. The extent to which the reference diet supports cognitive function across the life course, however, has not yet been evaluated. This Review assesses the evidence for diet supporting cognitive function from childhood into old age. A comprehensive but non-exhaustive literature search was done, synthesising studies that investigated the effect of whole foods on cognition in healthy, community-dwelling human participants. We found that the current evidence base is weak with mixed conclusions and multiple methodological caveats, which precludes strong conclusions pertaining to the suitability of dietary recommendations for each food group per age group. Long-term intervention and prospective cohort studies are needed to reduce this knowledge deficit. Revising dietary recommendations with the aim of maintaining an adequate nutrient intake to sustain healthy cognitive function across the life course could be worthwhile. This Review outlines recommendations for future work to help improve the current knowledge deficit regarding dietary intake and cognitive function across the life course and its implications for dietary guidelines such as the EAT-Lancet Commission.

To download this open-access article, please click here.

This work was commissioned by the Nutrition and Brain Health Task Force.

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Early Nutrition and Long-Term Health

Nutrition and Brain Health

Nutrition, Immunity and Inflammation

Prebiotics

Probiotics

GUT MICROBIOME AND HEALTH and NUTRITION AND CONSUMER SCIENCE

The gut and brain link via various metabolic and signalling pathways, each with the potential to influence mental, brain and cognitive health. Over the past decade, the involvement of the gut microbiota in gut-brain communication has become the focus of increased scientific interest, establishing the microbiota-gut-brain axis as a field of research. There is a growing number of association studies exploring the gut microbiota's possible role in memory, learning, anxiety, stress, neurodevelopmental and neurodegenerative disorders. Consequently, attention is now turning to how the microbiota can become the target of nutritional and therapeutic strategies for improved brain health and well-being. However, while such strategies that target the gut microbiota to influence brain health and function are currently under development with varying levels of success, still very little is yet known about the triggers and mechanisms underlying the gut microbiota's apparent influence on cognitive or brain function and most evidence comes from pre-clinical studies rather than well controlled clinical trials/investigations. Filling the knowledge gaps requires establishing a standardised methodology for human studies, including strong guidance for specific focus areas of the microbiota-gut-brain axis, the need for more extensive biological sample analyses, and identification of relevant biomarkers. Other urgent requirements are new advanced models for in vitro and in vivo studies of relevant mechanisms, and a greater focus on omics technologies with supporting bioinformatics resources (training, tools) to efficiently translate study findings, as well as the identification of relevant targets in study populations. The key to building a validated evidence base rely on increasing knowledge sharing and multi-disciplinary collaborations, along with continued public-private funding support. This will allow microbiota-gut-brain axis research to move to its next phase so we can identify realistic opportunities to modulate the microbiota for better brain health.

To download this open-access article, please click here.

This work was conducted in collaboration with the Early Nutrition and Long-Term Health, Nutrition and Brain Health, Nutrition, Immunity and Inflammation, Prebiotics and Probiotics Task Forces.

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Nutrition and Brain Health

NUTRITION, DEVELOPMENT& HEALTHY AGEING

The EAT-Lancet Commission devised a sustainable reference diet with the aim of reducing the incidence of non-communicable diseases and mortality globally while improving food system sustainability. The extent to which the reference diet supports cognitive function across the life course, however, has not yet been evaluated. This Review assesses the evidence for diet supporting cognitive function from childhood into old age. A comprehensive but non-exhaustive literature search was done, synthesising studies that investigated the effect of whole foods on cognition in healthy, community-dwelling human participants. We found that the current evidence base is weak with mixed conclusions and multiple methodological caveats, which precludes strong conclusions pertaining to the suitability of dietary recommendations for each food group per age group. Long-term intervention and prospective cohort studies are needed to reduce this knowledge deficit. Revising dietary recommendations with the aim of maintaining an adequate nutrient intake to sustain healthy cognitive function across the life course could be worthwhile. This Review outlines recommendations for future work to help improve the current knowledge deficit regarding dietary intake and cognitive function across the life course and its implications for dietary guidelines such as the EAT-Lancet Commission.

To download this open-access article, please click here.

This work was commissioned by the Nutrition and Brain Health Task Force.

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Multimedia

Completed Expert Groups