Health Benefits Assessment of Foods

Developing tools, guidance and supporting materials to scientifically substantiate health benefits of foods

Task Force Information

Objectives and list of Task Force members

Contact Information

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Activity Overview

Overview of ongoing and upcoming activities

Expert Groups

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Publications

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Task Force

Multimedia

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Completed Expert Groups

Details including experts involved of each activity

Task Force Information

Objectives

  • Develop guidance and tools to define the scientific substantiation of benefits of foods and food constituents for maintenance and improvement of health and wellness;
  • identify factors and compounds to help ensure health claims can meet regulatory standards;
  • help understand the role of the microbiome in metabolising food constituents and mediating health benefits of foods.

Task Force Members

NameAffiliationTitleCountry
Dr Matthias Sass – ChairADMDirector R&DDE
Prof. Kieran Tuohy – Co-ChairFondazione Edmund MachGroup Leader Nutrition & Nutrigenomics Research UnitIT
Dr Andrea BertoccoHerbalifeDirector Scientific AffairsUK
Prof. Jelena Helene Cvejic*University of Novi SadProfessorRS
Dr Pascale Fança-BerthonNaturex (Givaudan)Category Technical LeaderFR
Prof. Bryan Hanley*Academisch Centrum Tandheelkunde Amsterdam (ACTA)Visiting ResearcherNL
Dr Oliver HasselwanderIFFTechnical FellowUK
Mr Xavier LavigneAbbott NutritionDirector, Regulatory Policy & IntelligenceBE
Dr Alexandra MeynierMondelēz InternationalNutrition ScientistFR
Ms Naomi VenletILSI EuropeScientific Project ManagerBE

Contact Information

For more detailed information, please contact Naomi Venlet at nvenlet@ilsieurope.be or Luigi De Rosa at lderosa@ilsieurope.be

Activity Overview

Health benefits of polyphenols mediated by gut microbiome modulation and/or activity of microbial polyphenol-derived metabolites - Ongoing -

Objectives

The resulting systematic review will give a better understanding of the mechanism of action and characterisation of the food related polyphenols, as well as the required dose for health benefits. This review may help to design future human intervention studies.

Biological age assessment - Upcoming -

Objectives

Identify divergences between our chronological and biological clocks by focusing on our gut microbiome and correlate the microbiome’s biological ageing to dietary and lifestyle interventions.

Expert Groups

Health benefits of polyphenols mediated by gut microbiome modulation and/or activity of microbial polyphenol-derived metabolites

Background and Objectives

Polyphenol consumption (present in dark berries, cocoa, nuts and others) has been associated with several cardiometabolic and cognitive function benefits. However, the mechanism of action is often not fully understood. The objective is to better understand this mechanism, investigating the effects of consumption of food related polyphenols and microbial polyphenol-derived metabolites on the gut microbiome and associated health benefits.

Output

The resulting systematic review will give a better understanding of the mechanism of action and characterization of the food related polyphenols, as well as the required dose for health benefits. This review may help to design future human intervention studies.

Expert Group Members

Publications

All Publications

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Health Benefits Assessment of Foods

GUT MICROBIOME AND HEALTH

We performed a systematic review, meta-analysis, and meta-regression to determine if increasing daily protein ingestion contributes to gaining lean body mass (LBM), muscle strength, and physical/functional test performance in healthy subjects. A protocol for the present study was registered (PROSPERO, CRD42020159001), and a systematic search of Medline, Embase, CINAHL, and Web of Sciences databases was undertaken. Only randomized controlled trials (RCT) where participants increased their daily protein intake and were healthy and non-obese adults were included. Research questions focused on the main effects on the outcomes of interest and subgroup analysis, splitting the studies by participation in a resistance exercise (RE), age (<65 or ≥65 years old), and levels of daily protein ingestion. Three-level random-effects meta-analyses and meta-regressions were conducted on data from 74 RCT. Most of the selected studies tested the effects of additional protein ingestion during RE training. The evidence suggests that increasing daily protein ingestion may enhance gains in LBM in studies enrolling subjects in RE (SMD [standardized mean difference] = 0.22, 95% CI [95% confidence interval] 0.14:0.30, P < 0.01, 62 studies, moderate level of evidence). The effect on LBM was significant in subjects ≥65 years old ingesting 1.2-1.59 g of protein/kg/day and for younger subjects (<65 years old) ingesting ≥1.6 g of protein/kg/day submitted to RE. Lower-body strength gain was slightly higher by additional protein ingestion at ≥1.6 g of protein/kg/day during RE training (SMD = 0.40, 95% CI 0.09:0.35, P < 0.01, 19 studies, low level of evidence). Bench press strength is slightly increased by ingesting more protein in <65 years old subjects during RE training (SMD = 0.18, 95% CI 0.03:0.33, P = 0.01, 32 studies, low level of evidence). The effects of ingesting more protein are unclear when assessing handgrip strength and only marginal for performance in physical function tests. In conclusion, increasing daily protein ingestion results in small additional gains in LBM and lower body muscle strength gains in healthy adults enrolled in resistance exercise training. There is a slight effect on bench press strength and minimal effect performance in physical function tests. The effect on handgrip strength is unclear.

To download this open-access article, please click here.

This work was commissioned by the Health Benefits Assessment of Foods Task Force.

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Health Benefits Assessment of Foods

GUT MICROBIOME AND HEALTH

We performed a systematic review, meta-analysis, and meta-regression to determine if increasing daily protein ingestion contributes to gaining lean body mass (LBM), muscle strength, and physical/functional test performance in healthy subjects. A protocol for the present study was registered (PROSPERO, CRD42020159001), and a systematic search of Medline, Embase, CINAHL, and Web of Sciences databases was undertaken. Only randomized controlled trials (RCT) where participants increased their daily protein intake and were healthy and non-obese adults were included. Research questions focused on the main effects on the outcomes of interest and subgroup analysis, splitting the studies by participation in a resistance exercise (RE), age (<65 or ≥65 years old), and levels of daily protein ingestion. Three-level random-effects meta-analyses and meta-regressions were conducted on data from 74 RCT. Most of the selected studies tested the effects of additional protein ingestion during RE training. The evidence suggests that increasing daily protein ingestion may enhance gains in LBM in studies enrolling subjects in RE (SMD [standardized mean difference] = 0.22, 95% CI [95% confidence interval] 0.14:0.30, P < 0.01, 62 studies, moderate level of evidence). The effect on LBM was significant in subjects ≥65 years old ingesting 1.2-1.59 g of protein/kg/day and for younger subjects (<65 years old) ingesting ≥1.6 g of protein/kg/day submitted to RE. Lower-body strength gain was slightly higher by additional protein ingestion at ≥1.6 g of protein/kg/day during RE training (SMD = 0.40, 95% CI 0.09:0.35, P < 0.01, 19 studies, low level of evidence). Bench press strength is slightly increased by ingesting more protein in <65 years old subjects during RE training (SMD = 0.18, 95% CI 0.03:0.33, P = 0.01, 32 studies, low level of evidence). The effects of ingesting more protein are unclear when assessing handgrip strength and only marginal for performance in physical function tests. In conclusion, increasing daily protein ingestion results in small additional gains in LBM and lower body muscle strength gains in healthy adults enrolled in resistance exercise training. There is a slight effect on bench press strength and minimal effect performance in physical function tests. The effect on handgrip strength is unclear.

To download this open-access article, please click here.

This work was commissioned by the Health Benefits Assessment of Foods Task Force.

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Multimedia

Completed Expert Groups