Health Benefits Assessment of Foods

Health Benefits Assessment of Foods

Developing tools, guidance and supporting materials to scientifically substantiate health benefits of foods

Task Force Information

Objectives and list of Task Force members

Contact Information

Contact details in case you have specific questions

Activity Overview

Overview of ongoing and upcoming activities

Expert Groups

Objectives, output and list of experts involved in each activity

Publications

List of publications of this
Task Force

Multimedia

Links to Task Force related documents, recordings and much more...

Completed Expert Groups

Details including experts involved of each activity

Task Force Information

Objectives

• Develop guidance and tools to define the scientific substantiation of benefits of foods and food constituents for maintenance and improvement of health and wellness;
• identify factors and compounds to help ensure health claims can meet regulatory standards; help understand the role of the microbiome in metabolising food constituents and mediating health benefits of foods.

Task Force Members

Contact Information

For more detailed information, please contact Naomi Venlet at nvenlet@ilsieurope.be

Activity Overview

Ongoing

- Health benefits of polyphenols

The Expert Group is working on a systematic review that will give a better understanding of the mechanism of action and characterisation of the food related polyphenols, as well as the required dose for health benefits. This review may help to design future human intervention studies.

Start date: February 2020 | End date: Q1 2024

- Biological age assessment: are you as old as your gut says you are?

The Task Force is organising a workshop to identify divergences between our chronological and biological clocks by focusing on our gut microbiome and correlate the microbiome’s biological ageing to dietary and lifestyle interventions. The workshop will is taking place during the ILSI Europe Annual Symposium 2023 and a follow up report will be submitted for publication early 2024.

Start date: Q3 2023 | End date: Q1 2024

The Task Force will close after completing those two ongoing activities.

Expert Groups

Health benefits of polyphenols

Background and Objectives

Polyphenol consumption (present in dark berries, cocoa, nuts and others) has been associated with several cardiometabolic and cognitive function benefits. However, the mechanism of action is often not fully understood. The objective is to better understand this mechanism, investigating the effects of consumption of food related polyphenols and microbial polyphenol-derived metabolites on the gut microbiome and associated health benefits.

Output

The resulting systematic review will give a better understanding of the mechanism of action and characterization of the food related polyphenols, as well as the required dose for health benefits. This review may help to design future human intervention studies.

Expert Group Members

 

Biological age assessment: are you as old as your gut says you are?

Background and objectives
The interactive workshop aims to address the key questions, limitations and challenges on biological ageing in the context of the gut microbiota and its role in immunosenescence.

Objectives:

1. To identify the relationship of biological ageing and gut microbiota
2. What is the impact of the ageing gut microbiota on immunity?
3. How can we counteract the adverse effects of biological ageing, focussing on diet, and physical activity?

Speakers and Participanting Experts

  • Bryan Hanley, Academic Centre for Dentistry
    Amsterdam (ACTA), NL
  • Miguel Gueimonde, Spanish National Research
    Council, ES
  • Sonia Gonzalez, Universidad de Oviedo, ES
  • Philip Calder, University of Southampton, UK
  • Helene Jelena Cvejic, University of Novi Sad, RS
  • Isabelle Savary-Auzeloux, Human Nutrition Unit
    INRAE, FR

Organising Committee

  • Andrea Bertocco, Herbalife, UK
  • Helene Jelena Cvejic, University of Novi Sad, SRB
  • Kieran Tuohy, Fondazione Edmund Mach, UK
  • Bryan Hanley, ACTA, NL

Publications

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We performed a systematic review, meta-analysis, and meta-regression to determine if increasing daily protein ingestion contributes to gaining lean body mass (LBM), muscle strength, and physical/functional test performance in healthy subjects. A protocol for the present study was registered (PROSPERO, CRD42020159001), and a systematic search of Medline, Embase, CINAHL, and Web of Sciences databases was undertaken. Only randomized controlled trials (RCT) where participants increased their daily protein intake and were healthy and non-obese adults were included. Research questions focused on the main effects on the outcomes of interest and subgroup analysis, splitting the studies by participation in a resistance exercise (RE), age (<65 or ≥65 years old), and levels of daily protein ingestion. Three-level random-effects meta-analyses and meta-regressions were conducted on data from 74 RCT. Most of the selected studies tested the effects of additional protein ingestion during RE training. The evidence suggests that increasing daily protein ingestion may enhance gains in LBM in studies enrolling subjects in RE (SMD [standardized mean difference] = 0.22, 95% CI [95% confidence interval] 0.14:0.30, P < 0.01, 62 studies, moderate level of evidence). The effect on LBM was significant in subjects ≥65 years old ingesting 1.2-1.59 g of protein/kg/day and for younger subjects (<65 years old) ingesting ≥1.6 g of protein/kg/day submitted to RE. Lower-body strength gain was slightly higher by additional protein ingestion at ≥1.6 g of protein/kg/day during RE training (SMD = 0.40, 95% CI 0.09:0.35, P < 0.01, 19 studies, low level of evidence). Bench press strength is slightly increased by ingesting more protein in <65 years old subjects during RE training (SMD = 0.18, 95% CI 0.03:0.33, P = 0.01, 32 studies, low level of evidence). The effects of ingesting more protein are unclear when assessing handgrip strength and only marginal for performance in physical function tests. In conclusion, increasing daily protein ingestion results in small additional gains in LBM and lower body muscle strength gains in healthy adults enrolled in resistance exercise training. There is a slight effect on bench press strength and minimal effect performance in physical function tests. The effect on handgrip strength is unclear.


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Commissioned by the Health Benefits Assessment of Food  Task Force



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Multimedia

Introductory video

One-Pager

Completed Expert Groups

Overview of completed activities

- Review of the Evidence Base for Population Targeted Protein Intake for Muscle Health

- Identifying preferred approaches for quantifying the impact of modifying nutrient intakes

- Joint nutrition cluster activity on ‘mechanistic insights into the gut-brain axis' in collaboration with Early Nutrition and Long-Term Health; Nutrition, Immunity & Inflammation; Nutrition & Brain Health; Prebiotics and Probiotics Task Forces