Numerous studies have established that prebiotic ingredients in foods and dietary supplements may play a role in supporting human health. Over the three decades that have passed since prebiotics were first defined as a concept, research has revealed a complex universe of prebiotic-induced changes to the human microbiota. There are strong indications of a direct link between these prebiotic-induced changes and specific health benefits.
ILSI Europe Concise Monograph. 2013:1-32. Commissioned by the Prebiotics and Probiotics Task Forces. Translation available in Portuguese and Japanese.
Beneficial Microbes, 11 (5)- Pages: 411 – 455 (2020). Commissioned by the Prebiotics Task Force
Beneficial Microbes, 2022
Commissioned by the Prebiotics Task Force.
European Journal of Nutrition 2018;57(1):25-49. Commissioned by the Functional Foods and the Prebiotics Task Forces.
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Abstract
Numerous studies have established that prebiotic ingredients in foods and dietary supplements may play a role in supporting human health. Over the three decades that have passed since prebiotics were first defined as a concept, research has revealed a complex universe of prebiotic-induced changes to the human microbiota. There are strong indications of a direct link between these prebiotic-induced changes and specific health benefits. However, at the present time, the EU has not permitted use of the term 'prebiotic' in connection with an approved health claim. This paper is the outcome of a workshop organized on the 25th October 2023 by the European branch of the International Life Science Institute (ILSI). It provides an overview of the regulatory requirements for authorized health claims in the EU, key areas of prebiotic research, and findings to date in relation to prebiotics and digestive, immune, metabolic and cognitive health. Research gaps and documentation challenges are then explored and a roadmap proposed for achieving authorization of 'prebiotic' in the wording of future EU health claims.
Introductory video
One-pager
Read the full article
Commissioned by the Prebiotics Task Force
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Together with proteins and fats, carbohydrates are one of the macronutrients in the human diet. Digestible carbohydrates, such as starch, starch-based products, sucrose, lactose, glucose and some sugar alcohols and unusual (and fairly rare) α-linked glucans, directly provide us with energy while other carbohydrates including high molecular weight polysaccharides, mainly from plant cell walls, provide us with dietary fibre. Carbohydrates which are efficiently digested in the small intestine are not available in appreciable quantities to act as substrates for gut bacteria. Some oligo- and polysaccharides, many of which are also dietary fibres, are resistant to digestion in the small intestines and enter the colon where they provide substrates for the complex bacterial ecosystem that resides there. This review will focus on these non-digestible carbohydrates (NDC) and examine their impact on the gut microbiota and their physiological impact. Of particular focus will be the potential of non-digestible carbohydrates to act as prebiotics, but the review will also evaluate direct effects of NDC on human cells and systems
Keywords
Expand
Prebiotics, short-chain fatty acids (SCFA), non-digestible carbohydrates
To download this open-access article, please click here.
This work was commissioned by the Prebiotics Task Force.
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Abstract
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Introductory video
One-pager
Read the full article
Commissioned by the Prebiotics Task Force
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