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Workshop on Maternal Obesity, Diet, and Developmental Programming – Aligning Mother-Child Studies

Brussels, Belgium
10/10/2011 – 11/10/2011

The workshop organised by the Metabolic Imprinting Task Force aimed to identify the key outstanding questions in the area of ‘Early life nutritional determinants of offspring obesity and its metabolic complications’ and define the optimal methodological approaches to answer these questions.

The objective of the workshop was to answer the following questions:

  • Have we established an independent relationship between early life nutrition and offspring obesity and metabolic complications?
  • If so, have we established the most important determinant and mechanism of the relationship?
  • If not, what do we need to do to determine whether there is a relationship? Using existing data or setting up new mother-child studies.

Different methodological aspects was addressed:

  • Maternal dietary habits / status
  • Maternal body weight, composition, and lifestyle
  • Infant growth, body weight regulation and early risk factors

The outcome of the discussion will be collated in a scientific paper addressing how to improve mother-child study designs and make the best use of existing data.

PROGRAM AND PARTICIPANTS LIST

The program is available here.

The final participants list is available here.

SUMMARY

The workshop summary is available here.

PRESENTATIONS

SESSION 1: Maternal dietary exposures and offspring obesity and metabolic risk
The breadth and depth of evidence to suggest that maternal dietary intake is a determinant of offspring obesity and metabolic risk
M. Gillman, Harvard Medical School, US
(not available)

Southampton Women Survey (SWS, UK)
S. Robinson, University of Southampton, UK
PDF

The Norwegian Mother and Child Cohort Study (MoBa)
H. Margrete Meltzer, Norwegian Institute of Public Health, NO
PDF

The Danish National Birth Cohort: Maternal dietary exposures and offspring metabolic risk (DNBC)
S. Olsen, Statens Serum Institut, DK
PDF

Screening for Pregnancy Endpoints (SCOPE UK and IR)
L. Poston, King’s College London, UK
PDF

Generation R (NL)
V. Jaddoe, Erasmus University Rotterdam, NL
PDF

Project Viva (US)
M. Gillman, Harvard Medical School, US
(not available)

Mother-Child study in Crete (RHEA, GR)
L. Chatzi, University of Crete, GR
PDF

Fatty Acids during Pregnancy and Lactation and Body Fat Mass in Newborns (INFAT, DE)
H. Hauner, Technical University of Munich, DE
PDF

UK Pregnancies: Better Eating and Activity Trial (UPBEAT, UK)
L. Poston, King’s College London, UK
PDF

Wrap-Up Session
M. Mendez, Centre for research in environmental epidemiology – CREAL, ES
(not available)

SESSION 2: Maternal body weight, composition, and offspring obesity and metabolic risk
Maternal body weight/composition in obese mother; a relationship with obesity and metabolic risks for their offspring?
C. Campoy, University of Granada, ES
PDF

Maternal gestational weight gain; relationship with obesity risk in the offspring?
K. Godfrey, University of Southampton, UK
PDF

Don’t forget the genes’; determination of role of genetic variants and epigenetic processes in associations between mother and child obesity
K. Ong, University of Cambridge, UK
PDF

SESSION 3: Postnatal exposures, infant growth trajectories and relationships with infant and childhood obesity and metabolic risk
The Early Nutrition Project. Strategies to assess the role of pre- and postnatal exposures and growth trajectories on development of childhood obesity and metabolic risk
B. Koletzko, University of Munich, DE
(not available)

Screening for Pregnancy Endpoints (SCOPE, Auckland and SCOPE Ireland)
L. Kenny, University College Cork, IE
(not available)

Project Viva (US)
M. Gillman, Harvard Medical School, US
(not available)

Southampton Women Study (SWS, UK)
K. Godfrey, University of Southampton, UK
PDF