Scientific Publications

Scientific Publications

ILSI Europe disseminates science by publishing articles on original research, literature reviews and gap analyses, and meeting proceedings in peer-reviewed journals with high impact factors. ILSI Europe also publishes books, monographs, white papers, and other reports.

Discover below our latest scientific publications.

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                    [post_date] => 2022-06-29 09:16:43
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                    [post_content] => 

Nutrient Intake Optimisation

Adequate iodine intake is essential throughout life. Key dietary sources are iodized salt and animal products, but dietary patterns in Europe are changing, for example toward lower salt intake and a more plant-based diet.

The objective of this systematic review was to review iodine intake (not status) in European populations (adults, children, and pregnant women) to identify at-risk groups and dietary sources. In total, 57 studies were included, comprising 22 national surveys and 35 sub-national studies. Iodine intake data were available from national surveys of children aged <10 years (n = 11), 11-17 years (n = 12), and adults (n = 15), but data from pregnancy were only available from sub-national studies.

We show that iodine intake data are lacking-only 17 of 45 (38%) European countries had iodine-intake data from national surveys. Iodine intake reported from national surveys was below recommendations for: (1) children aged <10 years in 2 surveys (18%), (2) boys and girls aged 11-17 years in 6 (50%) and 8 (68%) surveys, respectively, and (3) adult men and women in 7 (47%) and 12 (80%) surveys, respectively. In pregnant women, intake was below recommendations except where women were taking iodine-containing supplements. Just 32% of national surveys (n = 7) included iodized salt when estimating iodine intake. Milk, dairy products, fish, and eggs were important contributors to intake in many countries, suggesting limited sources in plant-based diets.

Results are limited by the challenges of dietary assessment for measuring iodine intake. Future national surveys should include iodine intake. Policy makers should consider dietary sources alongside any iodized salt policies when considering methods for improving population iodine intake.

Keywords Expand

Adults, children, diet, Europe, fish, iodized, iodine, intake, milk, pregnancy

To download this open-access article, please click here.

This work was commissioned by the Nutrient Intake Optimisation Task Force.
[post_title] => A systematic review of iodine intake in children, adults, and pregnant women in Europe - comparison against dietary recommendations and evaluation of dietary iodine sources [post_excerpt] => [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => a-systematic-review-of-iodine-intake-in-children-adults-and-pregnant-women-in-europe-comparison-against-dietary-recommendations-and-evaluation-of-dietary-iodine-sources [to_ping] => [pinged] => [post_modified] => 2022-07-04 10:32:19 [post_modified_gmt] => 2022-07-04 10:32:19 [post_content_filtered] => [post_parent] => 0 [guid] => https://ilsi.eu/?post_type=publication&p=11103 [menu_order] => 0 [post_type] => publication [post_mime_type] => [comment_count] => 0 [filter] => raw ) [1] => WP_Post Object ( [ID] => 12002 [post_author] => 24 [post_date] => 2022-10-10 06:10:44 [post_date_gmt] => 2022-10-10 06:10:44 [post_content] =>

Humans often show variable responses to dietary, prebiotic, and probiotic interventions. Emerging evidence indicates that the gut microbiota is a key determinant for this population heterogeneity. Here, we provide an overview of some of the major computational and experimental tools being applied to critical questions of microbiota-mediated personalized nutrition and health. First, we discuss the latest advances in in silico modeling of the microbiota-nutrition-health axis, including the application of statistical, mechanistic, and hybrid artificial intelligence models. Second, we address high-throughput in vitro techniques for assessing inter-individual heterogeneity, from ex vivo batch culturing of stool and continuous culturing in anaerobic bioreactors, to more sophisticated organ-on-a-chip models that integrate both host and microbial compartments. Third, we explore in vivo approaches for better understanding personalized, microbiota-mediated responses to diet, prebiotics, and probiotics, from non-human animal models and human observational studies, to human feeding trials and crossover interventions. We highlight examples of existing, consumer-facing precision nutrition platforms that are currently leveraging the gut microbiota. Furthermore, we discuss how the integration of a broader set of the tools and techniques described in this piece can generate the data necessary to support a greater diversity of precision nutrition strategies. Finally, we present a vision of a precision nutrition and healthcare future, which leverages the gut microbiota to design effective, individual-specific interventions.

Download the full article here

or click on the image below to download the one-pager summary.

One-pager PRE PRO EG Prediction of indv. responses

Commissioned by the Prebiotics and Probiotics Task Forces.

[post_title] => Perspective: Leveraging the Gut Microbiota to Predict Personalized Responses to Dietary, Prebiotic, and Probiotic Interventions [post_excerpt] => [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => perspective-leveraging-the-gut-microbiota-to-predict-personalized-responses-to-dietary-prebiotic-and-probiotic-interventions [to_ping] => [pinged] => [post_modified] => 2023-02-03 13:12:13 [post_modified_gmt] => 2023-02-03 13:12:13 [post_content_filtered] => [post_parent] => 0 [guid] => https://ilsi.eu/?post_type=publication&p=12002 [menu_order] => 0 [post_type] => publication [post_mime_type] => [comment_count] => 0 [filter] => raw ) [2] => WP_Post Object ( [ID] => 11188 [post_author] => 24 [post_date] => 2022-07-04 11:37:57 [post_date_gmt] => 2022-07-04 11:37:57 [post_content] =>

Together with proteins and fats, carbohydrates are one of the macronutrients in the human diet. Digestible carbohydrates, such as starch, starch-based products, sucrose, lactose, glucose and some sugar alcohols and unusual (and fairly rare) α-linked glucans, directly provide us with energy while other carbohydrates including high molecular weight polysaccharides, mainly from plant cell walls, provide us with dietary fibre. Carbohydrates which are efficiently digested in the small intestine are not available in appreciable quantities to act as substrates for gut bacteria. Some oligo- and polysaccharides, many of which are also dietary fibres, are resistant to digestion in the small intestines and enter the colon where they provide substrates for the complex bacterial ecosystem that resides there. This review will focus on these non-digestible carbohydrates (NDC) and examine their impact on the gut microbiota and their physiological impact. Of particular focus will be the potential of non-digestible carbohydrates to act as prebiotics, but the review will also evaluate direct effects of NDC on human cells and systems

Keywords Expand

Prebiotics, short-chain fatty acids (SCFA), non-digestible carbohydrates

To download this open-access article, please click here.

This work was commissioned by the Prebiotics Task Force.

[post_title] => Structure and function of non-digestible carbohydrates in the gut microbiome [post_excerpt] => [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => structure-and-function-of-non-digestible-carbohydrates-in-the-gut-microbiome [to_ping] => [pinged] => [post_modified] => 2023-01-04 12:25:52 [post_modified_gmt] => 2023-01-04 12:25:52 [post_content_filtered] => [post_parent] => 0 [guid] => https://ilsi.eu/?post_type=publication&p=11188 [menu_order] => 0 [post_type] => publication [post_mime_type] => [comment_count] => 0 [filter] => raw ) [3] => WP_Post Object ( [ID] => 11860 [post_author] => 24 [post_date] => 2022-08-22 13:02:03 [post_date_gmt] => 2022-08-22 13:02:03 [post_content] =>

Please click here to access the Whitepaper

[post_title] => Whitepaper Report from the Webinar Cronobacter in the Spotlight: New Insights Into a Known Organism [post_excerpt] => [post_status] => publish [comment_status] => closed [ping_status] => closed [post_password] => [post_name] => whitepaper-report-from-the-webinar-published-in-food-magazine [to_ping] => [pinged] => [post_modified] => 2023-01-04 12:24:23 [post_modified_gmt] => 2023-01-04 12:24:23 [post_content_filtered] => [post_parent] => 0 [guid] => https://ilsi.eu/?post_type=publication&p=11860 [menu_order] => 0 [post_type] => publication [post_mime_type] => [comment_count] => 0 [filter] => raw ) [4] => WP_Post Object ( [ID] => 12148 [post_author] => 24 [post_date] => 2022-10-19 09:13:00 [post_date_gmt] => 2022-10-19 09:13:00 [post_content] =>

Nutrition and Brain Health

NUTRITION, DEVELOPMENT& HEALTHY AGEING

The EAT-Lancet Commission devised a sustainable reference diet with the aim of reducing the incidence of non-communicable diseases and mortality globally while improving food system sustainability. The extent to which the reference diet supports cognitive function across the life course, however, has not yet been evaluated. This Review assesses the evidence for diet supporting cognitive function from childhood into old age. A comprehensive but non-exhaustive literature search was done, synthesising studies that investigated the effect of whole foods on cognition in healthy, community-dwelling human participants. We found that the current evidence base is weak with mixed conclusions and multiple methodological caveats, which precludes strong conclusions pertaining to the suitability of dietary recommendations for each food group per age group. Long-term intervention and prospective cohort studies are needed to reduce this knowledge deficit. Revising dietary recommendations with the aim of maintaining an adequate nutrient intake to sustain healthy cognitive function across the life course could be worthwhile. This Review outlines recommendations for future work to help improve the current knowledge deficit regarding dietary intake and cognitive function across the life course and its implications for dietary guidelines such as the EAT-Lancet Commission.

To download this open-access article, please click here.

This work was commissioned by the Nutrition and Brain Health Task Force.

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Nutrient Intake Optimisation

Adequate iodine intake is essential throughout life. Key dietary sources are iodized salt and animal products, but dietary patterns in Europe are changing, for example toward lower salt intake and a more plant-based diet.

The objective of this systematic review was to review iodine intake (not status) in European populations (adults, children, and pregnant women) to identify at-risk groups and dietary sources. In total, 57 studies were included, comprising 22 national surveys and 35 sub-national studies. Iodine intake data were available from national surveys of children aged <10 years (n = 11), 11-17 years (n = 12), and adults (n = 15), but data from pregnancy were only available from sub-national studies.

We show that iodine intake data are lacking-only 17 of 45 (38%) European countries had iodine-intake data from national surveys. Iodine intake reported from national surveys was below recommendations for: (1) children aged <10 years in 2 surveys (18%), (2) boys and girls aged 11-17 years in 6 (50%) and 8 (68%) surveys, respectively, and (3) adult men and women in 7 (47%) and 12 (80%) surveys, respectively. In pregnant women, intake was below recommendations except where women were taking iodine-containing supplements. Just 32% of national surveys (n = 7) included iodized salt when estimating iodine intake. Milk, dairy products, fish, and eggs were important contributors to intake in many countries, suggesting limited sources in plant-based diets.

Results are limited by the challenges of dietary assessment for measuring iodine intake. Future national surveys should include iodine intake. Policy makers should consider dietary sources alongside any iodized salt policies when considering methods for improving population iodine intake.

Keywords Expand

Adults, children, diet, Europe, fish, iodized, iodine, intake, milk, pregnancy

To download this open-access article, please click here.

This work was commissioned by the Nutrient Intake Optimisation Task Force.
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