International Journal of Obesity (London). 2016;40(3):381-394.
Use of low energy sweeteners (LES) in place of sugar, in children and adults, leads to reduced calorie intake and body weight, and possibly also when comparing LES beverages to water.
For the first time, all available science was integrated into a single review to evaluate the real impact of LES, such as saccharin, aspartame, sucralose or stevia, on energy intake (EI) and body weight (BW) over the short- and long-term. A considerable weight of evidence confirmed that consuming LES instead of sugar helps reduce relative energy intake and body weight. The authors conducted systematic reviews of relevant studies in animals and humans consuming LES in a non-restricted diet. In total, 12 human prospective cohort studies, 228 comparisons in human intervention studies (short and long-term) and 90 animal studies were examined. The comparison between LES beverages and water is important because it shows that LES do not increase appetite. If anything, the evidence suggests that LES beverages reduced body weight more than water. One reason for this may be that switching from sugar-sweetened drinks to those with LES may be an easier and more acceptable dietary change to make than switching to water. Managing energy balance (i.e., energy intake vs. energy expenditure) well results in a steady body weight. On the contrary, eating an excessive amount of food causes an increase in body weight as this extra energy is stored in the body as adipose tissue (fat). Low energy sweeteners were developed for consumers looking for ways to reduce their sugar and energy intake.
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