Why nutrition in early life matters?
Task Force Information
Objectives
The Task Force aims at providing scientific evidence to support guidelines for maternal and infant nutrition to ensure life-time optimal health. It also identifies risk factors for obesity and other health consequences at the earliest stages of life.
Task Force Members
Dr Carolien van Loo-Bouwman – Chair | Yili Innovation Center Europe | Open Innovation Manager | NL |
Dr Euridice Castaneda Gutierrez – Vice-Chair | H&H | Science and Communication Manager | CH |
Prof. Susan Ozanne – Co-Chair | University of Cambridge | Professor | UK |
Dr Marieke Abrahamse-Berkeveld | Danone Nutricia Research | Senior Team Leader Growth & Development | NL |
Prof. Stewart Forsyth* | Independent | Consultant | UK |
Dr Patricia Iozzo* | Italian National Research Council | Researcher | IT |
Dr Renaud Mestdagh | Cargill | Senior Scientist Infant Nutrition | BE |
Dr Elena Oliveros | Abbott Nutrition | Senior Scientist | ES |
Dr Linette Pellis | Ausnutria | Research Scientist | NL |
Dr Janna van Diepen | Reckitt Benckiser/Mead Johnson Nutrition | Senior Scientist | NL |
Ms Ching-Yu Chang | ILSI Europe | Scientific Project Manager | BE |
Contact Information
For more detailed information, please contact Ching-Yu Chang at cchang@ilsieurope.be or Belinda Antonio at bantonio@ilsieurope.be
Activity Overview
Body composition early in life and long-term health - Ongoing -
Objectives
This activity will review the available evidence on the factors that influence body composition during fatal life, infancy and childhood and on the association of body composition with long-term health outcomes. In addition, a gap analysis will be performed to outline future research needs.
Early biomarkers for prediction of metabolic health - Ongoing -
Objectives
The aim of the activity is to review biomarkers in early life that could be used to predict development of childhood obesity and metabolic health. This prediction may drive development and knowledge of personalized (infant) nutrition. The focus of the activity will be on both invasive and non-invasive, perinatal and postnatal biomarkers.
Lipid quality in early life nutrition - Upcoming -
Objectives
The activity aims to generate an overview of the dietary lipid quality in the first year of life and to what extent this brings or relates to health benefits to its consumers with a particular focus on exploring appropriate intake levels of SFA and MUFA.
Expert results
Peer-reviewed journal article (‘white paper’).
The content will cover expert insights and hopefully a concluding consensus on the FA profile of first year of life diet. It will identify knowledge gaps and outline plans for future research and possibly a basis for new EFSA recommendations.
Expert Groups
Review and Gap Analysis of Factors Affecting Body Composition in Fetal Life, Infancy and Childhood and Association to Long-Term Health
Background and Objectives
The clinical significance of differences in body composition (fat, bone and muscle) during fatal life, infancy and childhood on long-term health is currently not known. This activity aims to: review current evidence on the impact of life factors on body composition during infancy and childhood; test for association between body composition at infancy and childhood and long term health outcomes; Perform a gap analysis outlining areas where evidence needs to be generated
Output
These data will be compiled in a peer-reviewed publication with the purpose of informing scientists, policy makers and other stakeholders on knowledge gaps and research directions. Further, the outcomes will provide insight on critical periods of life where body composition measurement should be included to identify at-risk populations.
Expert Group Members
Prof. Neena Modi – Chair | Imperial College London | Professor of Neonatal Medicine | UK |
Dr Euridice Castaneda Gutierrez – Vice-Chair | H&H | Science and Communication Manager | CH |
Dr Marieke Abrahamse-Berkeveld | Danone Nutricia Research | Senior Team Leader Growth & Development | NL |
Dr Federica Amati | Imperial College London | Research Assistant | UK |
Dr Elena Oliveros | Abbott Nutrition | Senior Scientist | ES |
Prof. Susan Ozanne | University of Cambridge | Professor | UK |
Prof. Michael Symonds | University of Nottingham | Head of The Academic Division Child Health | UK |
Dr Carolien van Loo-Bouwmman | Yili Innovation Center Europe | Open Innovation Manager | NL |
Ms Ching-Yu Chang | ILSI Europe | Scientific Project Manager | BE |
Scientific review on biomarkers in early life (prenatal - infancy) to predict childhood obesity risk and metabolic health
Background and Objectives
The aim of the activity is to review biomarkers in early life that could be used to predict development of childhood obesity and metabolic health. The activity will focus on invasive and non-invasive, perinatal and postnatal biomarkers. This activity aims to:
- Summarise the current evidence for early life (perinatal and postnatal) biomarkers that are able to predict childhood obesity and related metabolic health
- Emphasise relevance of combining conventional predictive markers (e.g. early weight gain) with novel applications of metabolomics, epigenetics and microbiota profiling. It will help to more accurately and effectively identify infants at risk to develop obesity
- Emphasise importance of validity and reliability of identified biomarkers for application of such biomarkers in (daily) practice.
Output
The highlighted (recent) findings in the development of biomarkers for early life prediction of metabolic health could be used to guide risk prediction and stratification. This prediction may drive development and knowledge of personalised (infant) nutrition to reduce the risk of childhood obesity. Researchers should become aware of the urgency to develop and validate new predictive biomarkers that are both easily detectable and responsive to nutritional interventions.
Expert Group Members
Prof. Romy Gaillard – Chair | Erasmus University Rotterdam | Professor | NL |
Dr Janna van Diepen – Vice Chair | Reckitt Benckiser/Mead Johnson Nutrition | Senior Scientist | NL |
Dr Sophia Blaauwendraad | Erasmus University Rotterdam | Researcher | NL |
Dr Maria Carmen Collado | Institute of Agrochemistry and Food Technology | Professor | ES |
Prof. Angel Gil | University of Granada | Professor | ES |
Dr Patricia Iozzo | Italian National Research Council | Researcher | IT |
Dr Linette Pellis | Ausnutria | Research Scientist | NL |
Dr Francisco Javier Ruiz-Ojeda | University of Granada | RG Adipocytes and Metabolism group collaborator | ES |
Dr Carolien van Loo-Bouwman | Yili Innovation Center Europe | Open Innovation Manager | NL |
Ms Ching-Yu Chang | ILSI Europe | Scientific Project Manager | BE |
Publications
Z to A
Is there Evidence for Bacterial Transfer via the Placenta and any Role in the Colonization of the Infant Gut? – a Systematic Review
2020
Gestational Diabetes Mellitus and Diet: A Systematic Review and Meta-analysis of Randomized Controlled Trials Examining the Impact of Modified Dietary Interventions on Maternal Glucose Control and Neonatal Birth Weight.
2018
Diabetes Care 2018;41:1346–1361. Commissioned by the Early Nutrition and Long Term Health and the Obesity and Diabetes Task Forces.
Early Life Nutritional Programming of Obesity: Mother-Child Cohort Studies
2013
Annals of Nutrition and Metabolism. 2013;62:137-145. Commissioned by the Metabolic Imprinting Task Force.
A Systematic Review of the Effects of Increasing Arachidonic Acid Intake on PUFA Status, Metabolism and Health-Related Outcomes in Humans
2019
British Journal of Nutrition 2019. Commissioned by the Early Nutrition and Long Term Health and Nutrient Intake Optimisation Task Forces.
Multimedia
- Early Nutrition and Long-Term Health Task Force - One-pager
- The Early Nutrition and Long-Term Health Task Force in a nutshell, an introductory video*
* The video was developed on the occasion of the Annual Symposium
Workshop ‘Health Relevance of Lowering Postprandial Glycaemia in Children and Adolescents through Diet’
Watch the recordings
Completed Expert Groups
Overview of completed activities since 2021