New Approach Methodologies (NAMs)

New Approach Methodologies (NAMs)

JOINING FORCES FOR THE REPLACEMENT OF ANIMAL STUDIES IN FOOD SCIENCES

Task Force Information

Objectives and list of Task Force members

Contact Information

Contact details in case you have specific questions

Activity Overview

Overview of ongoing and upcoming activities

Expert Groups

Objectives, output and list of experts involved in each activity

Publications

List of publications of this
Task Force

Multimedia

Links to Task Force related documents, recordings and much more...

Completed Expert Groups

Details including experts involved of each activity

Task Force Information

Objectives

This unique transversal and multi-stakeholder Task Force aims to:

  • review the recently developed methods and build a consensus on how and what is needed to reduce animal testing in food and beverage development;
  • provide evidence-based science and evaluate potential strategies and approaches that ultimately could replace animal testing in food sciences;
  • communicate and disseminate the opportunities for alternatives in the food and drink sector.

Task Force Members

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Contact Information

For more detailed information, please contact Geraldine Borja at gborja@ilsieurope.be 

Activity Overview

Ongoing

- What Are the Challenges to Use Vital Human Material as an Innovative Approach to Move Towards Human-Based Science and Avoid Animal Research & Testing?

Identify existing tools and approaches that are not reliant on generating data in animals for safety evaluation in the food, nutrition and beverage sector. The outputs of this activity (case studies and roadmap) will be disseminated via a peer-reviewed publication, and shared with national and international authorities probably through a workshop.

Start date: Q3 2021 - End date: Q1 2026

In the pipeline

- Mapping the stakeholders’ landscape relevant to NAMs in the Food and Beverage sector.

- Facilitating multistakeholder consensus on international principles and criteria to adopt NAMs. The principles would outline the importance of e.g. technical performance criteria and human biological relevance criteria.

- Developing a code of conduct and best practice for facilitating data sharing between stakeholder groups.

- Developing case studies to demonstrate how NAMs can be applied in food safety assessment. The case studies would rely on real-world data to evaluate the scientific robustness, regulatory applicability, human relevance and cost-effectiveness of NAMs. They will also compare NAMs with existing approaches to identify differences in outcomes and highlight any gaps that need to be addressed to support wider implementation in the food sector.

Expert Groups

What Are the Challenges to Use Vital Human Material as an Innovative Approach to Move Towards Human-Based Science and Avoid Animal Research and Testing?

Background and Objectives
The translational value from animal to human physiology is questioned. The use of human material (e.g. tissues) offers a sensible opportunity for better extrapolation of safety and efficacy outcomes to humans. But several barriers and constraints exist to their feasibility and acceptance. The activity aims therefore to lead the discussion by proposing concrete actions to overcome these challenges and promote the use of human vital tissues to improve translational research. Overall, this project will contribute to the transition from animal-based to human-based safety evaluation in the food, nutrition and beverage sector. 

Output

This activity will enable the set-up of a roadmap for a network/infrastructure in Europe to make human vital tissue available for (biomedical) research (academia, public sector and industry), that can be used as an example to follow. An important output of this activity will be a peer-reviewed publication setting out the barriers and constraints and highlight gaps and needs to encourage/promote the use of human tissues as an alternative to animal testing 

Expert Group Members

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Publications

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Multimedia

One-Pager

Completed Expert Groups

- Holistic Approaches to Develop Alternative Strategies that do not Rely on Additional Animal Testing