ILSI Europe disseminates science by publishing articles on original research, literature reviews and gap analyses, and meeting proceedings in peer-reviewed journals with high impact factors. ILSI Europe also publishes books, monographs, white papers, and other reports.
Discover below our latest scientific publications.
Publication Date
All Publications
Allergen quantitative risk assessment within food operations: Concepts towards development of practical guidance based on an ILSI Europe workshop
Food Control, 2022
- ILSI Europe
Commissioned by the Food Allergy Task Force.
The role of endogenous versus exogenous sources in the exposome of putative genotoxins and consequences for risk assessment
Archives of Toxicology, 2022
- ILSI Europe
Commissioned by the Food Contaminants Task Force.
Systematic review and meta-analysis of protein intake to support muscle mass and function in healthy adults
Journal of Cachexia, Sarcopenia and Muscle, 2022
- ILSI Europe
Commissioned by the Heath Benefits Assessment of Foods Task Force.
Guidance in selecting analytical techniques for identification and quantification of non-intentionally added substances (NIAS) in food contact materials (FCMS)
2022
- ILSI Europe
Food Additives and Contaminants: Part A. 2022. Commissioned by the Packaging Materials Task Force.
The microbiota–gut–brain axis: pathways to better brain health. Perspectives on what we know, what we need to investigate and how to put knowledge into practice
Cellular and Molecular Life Sciences, 2022
- ILSI Europe
(2022) 79:80. Commissioned by the Early Nutrition and Long-Term Health, Nutrition and Brain Health, Nutrition, Immunity and Inflammation, Prebiotics and Probiotics Task Forces.
WP_Query Object
(
[query] => Array
(
[post_type] => publication
[posts_per_page] => 5
[type] =>
[area] =>
[committee] =>
[authors] =>
[showtitle] =>
[meta_query] => Array
(
[relation] => AND
)
[tax_query] => Array
(
)
[paged] => 6
[meta_key] => _ilsi_date
[orderby] => meta_value
[order] => DESC
)
[query_vars] => Array
(
[post_type] => publication
[posts_per_page] => 5
[type] =>
[area] =>
[committee] =>
[authors] =>
[showtitle] =>
[meta_query] => Array
(
[relation] => AND
)
[tax_query] => Array
(
)
[paged] => 6
[meta_key] => _ilsi_date
[orderby] => meta_value
[order] => DESC
[error] =>
[m] =>
[p] => 0
[post_parent] =>
[subpost] =>
[subpost_id] =>
[attachment] =>
[attachment_id] => 0
[name] =>
[pagename] =>
[page_id] => 0
[second] =>
[minute] =>
[hour] =>
[day] => 0
[monthnum] => 0
[year] => 0
[w] => 0
[category_name] =>
[tag] =>
[cat] =>
[tag_id] =>
[author] =>
[author_name] =>
[feed] =>
[tb] =>
[meta_value] =>
[preview] =>
[s] =>
[sentence] =>
[title] =>
[fields] =>
[menu_order] =>
=>
[category__in] => Array
(
)
[category__not_in] => Array
(
)
[category__and] => Array
(
)
[post__in] => Array
(
)
[post__not_in] => Array
(
)
[post_name__in] => Array
(
)
[tag__in] => Array
(
)
[tag__not_in] => Array
(
)
[tag__and] => Array
(
)
[tag_slug__in] => Array
(
)
[tag_slug__and] => Array
(
)
[post_parent__in] => Array
(
)
[post_parent__not_in] => Array
(
)
[author__in] => Array
(
)
[author__not_in] => Array
(
)
[search_columns] => Array
(
)
[ignore_sticky_posts] =>
[suppress_filters] =>
[cache_results] => 1
[update_post_term_cache] => 1
[update_menu_item_cache] =>
[lazy_load_term_meta] => 1
[update_post_meta_cache] => 1
[nopaging] =>
[comments_per_page] => 50
[no_found_rows] =>
)
[tax_query] => WP_Tax_Query Object
(
[queries] => Array
(
)
[relation] => AND
[table_aliases:protected] => Array
(
)
[queried_terms] => Array
(
)
[primary_table] => wp_3_posts
[primary_id_column] => ID
)
[meta_query] => WP_Meta_Query Object
(
[queries] => Array
(
[0] => Array
(
[key] => _ilsi_date
)
[relation] => OR
)
[relation] => AND
[meta_table] => wp_3_postmeta
[meta_id_column] => post_id
[primary_table] => wp_3_posts
[primary_id_column] => ID
[table_aliases:protected] => Array
(
[0] => wp_3_postmeta
)
[clauses:protected] => Array
(
[wp_3_postmeta] => Array
(
[key] => _ilsi_date
[compare] => =
[compare_key] => =
[alias] => wp_3_postmeta
[cast] => CHAR
)
)
[has_or_relation:protected] =>
)
[date_query] =>
[request] => SELECT SQL_CALC_FOUND_ROWS wp_3_posts.ID
FROM wp_3_posts INNER JOIN wp_3_postmeta ON ( wp_3_posts.ID = wp_3_postmeta.post_id )
WHERE 1=1 AND (
wp_3_postmeta.meta_key = '_ilsi_date'
) AND ((wp_3_posts.post_type = 'publication' AND (wp_3_posts.post_status = 'publish' OR wp_3_posts.post_status = 'acf-disabled')))
GROUP BY wp_3_posts.ID
ORDER BY wp_3_postmeta.meta_value DESC
LIMIT 25, 5
[posts] => Array
(
[0] => WP_Post Object
(
[ID] => 10663
[post_author] => 24
[post_date] => 2022-04-13 16:14:07
[post_date_gmt] => 2022-04-13 16:14:07
[post_content] =>
Food Allergy Task Force
NEW APPROACHES FOR FOOD SAFETY
Quantitative risk assessment (QRA) for allergens exists in many different forms with different requirements placed on the risk assessor depending on the question that needs to be answered. An electronic workshop held in October 2020 and comprising representatives from a wide range of food allergy and allergen stakeholder groups identified that a summary of current best in class guidance, identified gaps, potential improvements & harmonization of allergen QRA arising largely from cross contact would be very beneficial. The current manuscript provides an introduction to allergen QRA and an overview of inputs potentially needed for different QRA methods, when deemed feasible and necessary. It also introduces the European branch of the International Life Sciences Institute (ILSI Europe) Expert Group (EG), created to attempt to achieve consensus on the methodologies needed for allergen QRAs by food business operators, and their implementation. Areas of focus include proactive assessments for food production under normal conditions, both in the upstream supply chain and in food production facilities, and reactive assessments as part of an allergen incident response. As a follow-up report to the October 2020 electronic workshop, the current manuscript provides an overview of allergen QRA and insights into the guidance being developed. This manuscript will itself be followed by more detailed guidance for allergen QRA published open access as an ILSI Europe report.
Link to download the full-text
Keywords
Expand
Allergens; Quantitative risk assessment (QRA); Supply chain; Incidents; Cross-contact; Precautionary allergen labelling (PAL)
[post_title] => Allergen quantitative risk assessment within food operations: Concepts towards development of practical guidance based on an ILSI Europe workshop
[post_excerpt] =>
[post_status] => publish
[comment_status] => closed
[ping_status] => closed
[post_password] =>
[post_name] => allergen-quantitative-risk-assessment-within-food-operations-concepts-towards-development-of-practical-guidance-based-on-an-ilsi-europe-workshop
[to_ping] =>
[pinged] =>
[post_modified] => 2023-01-04 11:38:08
[post_modified_gmt] => 2023-01-04 11:38:08
[post_content_filtered] =>
[post_parent] => 0
[guid] => https://ilsi.eu/?post_type=publication&p=10663
[menu_order] => 0
[post_type] => publication
[post_mime_type] =>
[comment_count] => 0
[filter] => raw
)
[1] => WP_Post Object
(
[ID] => 10609
[post_author] => 24
[post_date] => 2022-03-29 08:35:38
[post_date_gmt] => 2022-03-29 08:35:38
[post_content] =>
The "totality" of the human exposure is conceived to encompass life-associated endogenous and exogenous aggregate exposures. Process-related contaminants (PRCs) are not only formed in foods by heat processing, but also occur endogenously in the organism as physiological components of energy metabolism, potentially also generated by the human microbiome. To arrive at a comprehensive risk assessment, it is necessary to understand the contribution of in vivo background occurrence as compared to the ingestion from exogenous sources. Hence, this review provides an overview of the knowledge on the contribution of endogenous exposure to the overall exposure to putative genotoxic food contaminants, namely ethanol, acetaldehyde, formaldehyde, acrylamide, acrolein, α,β-unsaturated alkenals, glycation compounds, N-nitroso compounds, ethylene oxide, furans, 2- and 3-MCPD, and glycidyl esters. The evidence discussed herein allows to conclude that endogenous formation of some contaminants appears to contribute substantially to the exposome. This is of critical importance for risk assessment in the cases where endogenous exposure is suspected to outweigh the exogenous one (e.g. formaldehyde and acrolein).
Link to download the full-text
Keywords
Expand
Endogenous exposure; Exposome; Genotoxins; Process-related contaminants
Commissioned by the Food Contaminants Task Force.
[post_title] => The role of endogenous versus exogenous sources in the exposome of putative genotoxins and consequences for risk assessment
[post_excerpt] =>
[post_status] => publish
[comment_status] => closed
[ping_status] => closed
[post_password] =>
[post_name] => the-role-of-endogenous-versus-exogenous-sources-in-the-exposome-of-putative-genotoxins-and-consequences-for-risk-assessment
[to_ping] =>
[pinged] =>
[post_modified] => 2023-01-04 16:20:28
[post_modified_gmt] => 2023-01-04 16:20:28
[post_content_filtered] =>
[post_parent] => 0
[guid] => https://ilsi.eu/?post_type=publication&p=10609
[menu_order] => 0
[post_type] => publication
[post_mime_type] =>
[comment_count] => 0
[filter] => raw
)
[2] => WP_Post Object
(
[ID] => 10634
[post_author] => 24
[post_date] => 2022-04-07 15:28:06
[post_date_gmt] => 2022-04-07 15:28:06
[post_content] =>
We performed a systematic review, meta-analysis, and meta-regression to determine if increasing daily protein ingestion contributes to gaining lean body mass (LBM), muscle strength, and physical/functional test performance in healthy subjects. A protocol for the present study was registered (PROSPERO, CRD42020159001), and a systematic search of Medline, Embase, CINAHL, and Web of Sciences databases was undertaken. Only randomized controlled trials (RCT) where participants increased their daily protein intake and were healthy and non-obese adults were included. Research questions focused on the main effects on the outcomes of interest and subgroup analysis, splitting the studies by participation in a resistance exercise (RE), age (<65 or ≥65 years old), and levels of daily protein ingestion. Three-level random-effects meta-analyses and meta-regressions were conducted on data from 74 RCT. Most of the selected studies tested the effects of additional protein ingestion during RE training. The evidence suggests that increasing daily protein ingestion may enhance gains in LBM in studies enrolling subjects in RE (SMD [standardized mean difference] = 0.22, 95% CI [95% confidence interval] 0.14:0.30, P < 0.01, 62 studies, moderate level of evidence). The effect on LBM was significant in subjects ≥65 years old ingesting 1.2-1.59 g of protein/kg/day and for younger subjects (<65 years old) ingesting ≥1.6 g of protein/kg/day submitted to RE. Lower-body strength gain was slightly higher by additional protein ingestion at ≥1.6 g of protein/kg/day during RE training (SMD = 0.40, 95% CI 0.09:0.35, P < 0.01, 19 studies, low level of evidence). Bench press strength is slightly increased by ingesting more protein in <65 years old subjects during RE training (SMD = 0.18, 95% CI 0.03:0.33, P = 0.01, 32 studies, low level of evidence). The effects of ingesting more protein are unclear when assessing handgrip strength and only marginal for performance in physical function tests. In conclusion, increasing daily protein ingestion results in small additional gains in LBM and lower body muscle strength gains in healthy adults enrolled in resistance exercise training. There is a slight effect on bench press strength and minimal effect performance in physical function tests. The effect on handgrip strength is unclear.
Download the full open-access article here
or click on the image below to download the one-pager summary.
Commissioned by the Health Benefits Assessment of Food Task Force
[post_title] => Systematic review and meta-analysis of protein intake to support muscle mass and function in healthy adults
[post_excerpt] =>
[post_status] => publish
[comment_status] => closed
[ping_status] => closed
[post_password] =>
[post_name] => systematic-review-and-meta-analysis-of-protein-intake-to-support-muscle-mass-and-function-in-healthy-adults
[to_ping] =>
[pinged] =>
[post_modified] => 2023-01-27 15:48:19
[post_modified_gmt] => 2023-01-27 15:48:19
[post_content_filtered] =>
[post_parent] => 0
[guid] => https://ilsi.eu/?post_type=publication&p=10634
[menu_order] => 0
[post_type] => publication
[post_mime_type] =>
[comment_count] => 0
[filter] => raw
)
[3] => WP_Post Object
(
[ID] => 10611
[post_author] => 24
[post_date] => 2022-03-29 12:31:37
[post_date_gmt] => 2022-03-29 12:31:37
[post_content] =>
Packaging Materials Task Force
SMART PACKAGING
There are numerous approaches and methodologies for assessing the identity and quantities of non-intentionally added substances (NIAS) in food contact materials (FCMs). They can give different results and it can be difficult to make meaningful comparisons. The initial approach was to attempt to prepare a prescriptive methodology but as this proved impossible; this paper develops guidelines that need to be taken into consideration when assessing NIAS. Different approaches to analysing NIAS in FCMs are reviewed and compared. The approaches for preparing the sample for analysis, recommended procedures for screening, identification, and quantification of NIAS as well as the reporting requirements are outlined. Different analytical equipment and procedures are compared. Limitations of today's capabilities are raised along with some research needs.
Link to download the full-text
Keywords
Expand
Food contact materials; NIAS; chromatographic methods; food packaging; migration; non-intentionally added substances; plastics
[post_title] => Guidance in selecting analytical techniques for identification and quantification of non-intentionally added substances (NIAS) in food contact materials (FCMS)
[post_excerpt] =>
[post_status] => publish
[comment_status] => closed
[ping_status] => closed
[post_password] =>
[post_name] => guidance-in-selecting-analytical-techniques-for-identification-and-quantification-of-non-intentionally-added-substances-nias-in-food-contact-materials-fcms
[to_ping] =>
[pinged] =>
[post_modified] => 2022-06-15 07:54:30
[post_modified_gmt] => 2022-06-15 07:54:30
[post_content_filtered] =>
[post_parent] => 0
[guid] => https://ilsi.eu/?post_type=publication&p=10611
[menu_order] => 0
[post_type] => publication
[post_mime_type] =>
[comment_count] => 0
[filter] => raw
)
[4] => WP_Post Object
(
[ID] => 10456
[post_author] => 24
[post_date] => 2022-03-28 13:12:46
[post_date_gmt] => 2022-03-28 13:12:46
[post_content] =>
Early Nutrition and Long-Term Health
Nutrition and Brain Health
Nutrition, Immunity and Inflammation
Prebiotics
Probiotics
GUT MICROBIOME AND HEALTH and NUTRITION AND CONSUMER SCIENCE
The gut and brain link via various metabolic and signalling pathways, each with the potential to influence mental, brain and cognitive health. Over the past decade, the involvement of the gut microbiota in gut-brain communication has become the focus of increased scientific interest, establishing the microbiota-gut-brain axis as a field of research. There is a growing number of association studies exploring the gut microbiota's possible role in memory, learning, anxiety, stress, neurodevelopmental and neurodegenerative disorders. Consequently, attention is now turning to how the microbiota can become the target of nutritional and therapeutic strategies for improved brain health and well-being. However, while such strategies that target the gut microbiota to influence brain health and function are currently under development with varying levels of success, still very little is yet known about the triggers and mechanisms underlying the gut microbiota's apparent influence on cognitive or brain function and most evidence comes from pre-clinical studies rather than well controlled clinical trials/investigations. Filling the knowledge gaps requires establishing a standardised methodology for human studies, including strong guidance for specific focus areas of the microbiota-gut-brain axis, the need for more extensive biological sample analyses, and identification of relevant biomarkers. Other urgent requirements are new advanced models for in vitro and in vivo studies of relevant mechanisms, and a greater focus on omics technologies with supporting bioinformatics resources (training, tools) to efficiently translate study findings, as well as the identification of relevant targets in study populations. The key to building a validated evidence base rely on increasing knowledge sharing and multi-disciplinary collaborations, along with continued public-private funding support. This will allow microbiota-gut-brain axis research to move to its next phase so we can identify realistic opportunities to modulate the microbiota for better brain health.
To download this open-access article, please click here.
This work was conducted in collaboration with the Early Nutrition and Long-Term Health, Nutrition and Brain Health, Nutrition, Immunity and Inflammation, Prebiotics and Probiotics Task Forces.
[post_title] => The microbiota–gut–brain axis: pathways to better brain health. Perspectives on what we know, what we need to investigate and how to put knowledge into practice
[post_excerpt] =>
[post_status] => publish
[comment_status] => closed
[ping_status] => closed
[post_password] =>
[post_name] => the-microbiota-gut-brain-axis-pathways-to-better-brain-health-perspectives-on-what-we-know-what-we-need-to-investigate-and-how-to-put-knowledge-into-practice
[to_ping] =>
[pinged] =>
[post_modified] => 2022-10-10 06:51:51
[post_modified_gmt] => 2022-10-10 06:51:51
[post_content_filtered] =>
[post_parent] => 0
[guid] => https://ilsi.eu/?post_type=publication&p=10456
[menu_order] => 0
[post_type] => publication
[post_mime_type] =>
[comment_count] => 0
[filter] => raw
)
)
[post_count] => 5
[current_post] => -1
[before_loop] =>
[in_the_loop] =>
[post] => WP_Post Object
(
[ID] => 10663
[post_author] => 24
[post_date] => 2022-04-13 16:14:07
[post_date_gmt] => 2022-04-13 16:14:07
[post_content] =>
Food Allergy Task Force
NEW APPROACHES FOR FOOD SAFETY
Quantitative risk assessment (QRA) for allergens exists in many different forms with different requirements placed on the risk assessor depending on the question that needs to be answered. An electronic workshop held in October 2020 and comprising representatives from a wide range of food allergy and allergen stakeholder groups identified that a summary of current best in class guidance, identified gaps, potential improvements & harmonization of allergen QRA arising largely from cross contact would be very beneficial. The current manuscript provides an introduction to allergen QRA and an overview of inputs potentially needed for different QRA methods, when deemed feasible and necessary. It also introduces the European branch of the International Life Sciences Institute (ILSI Europe) Expert Group (EG), created to attempt to achieve consensus on the methodologies needed for allergen QRAs by food business operators, and their implementation. Areas of focus include proactive assessments for food production under normal conditions, both in the upstream supply chain and in food production facilities, and reactive assessments as part of an allergen incident response. As a follow-up report to the October 2020 electronic workshop, the current manuscript provides an overview of allergen QRA and insights into the guidance being developed. This manuscript will itself be followed by more detailed guidance for allergen QRA published open access as an ILSI Europe report.
Link to download the full-text
Keywords
Expand
Allergens; Quantitative risk assessment (QRA); Supply chain; Incidents; Cross-contact; Precautionary allergen labelling (PAL)
[post_title] => Allergen quantitative risk assessment within food operations: Concepts towards development of practical guidance based on an ILSI Europe workshop
[post_excerpt] =>
[post_status] => publish
[comment_status] => closed
[ping_status] => closed
[post_password] =>
[post_name] => allergen-quantitative-risk-assessment-within-food-operations-concepts-towards-development-of-practical-guidance-based-on-an-ilsi-europe-workshop
[to_ping] =>
[pinged] =>
[post_modified] => 2023-01-04 11:38:08
[post_modified_gmt] => 2023-01-04 11:38:08
[post_content_filtered] =>
[post_parent] => 0
[guid] => https://ilsi.eu/?post_type=publication&p=10663
[menu_order] => 0
[post_type] => publication
[post_mime_type] =>
[comment_count] => 0
[filter] => raw
)
[comment_count] => 0
[current_comment] => -1
[found_posts] => 436
[max_num_pages] => 88
[max_num_comment_pages] => 0
[is_single] =>
[is_preview] =>
[is_page] =>
[is_archive] =>
[is_date] =>
[is_year] =>
[is_month] =>
[is_day] =>
[is_time] =>
[is_author] =>
[is_category] =>
[is_tag] =>
[is_tax] =>
[is_search] =>
[is_feed] =>
[is_comment_feed] =>
[is_trackback] =>
[is_home] => 1
[is_privacy_policy] =>
[is_404] =>
[is_embed] =>
[is_paged] => 1
[is_admin] =>
[is_attachment] =>
[is_singular] =>
[is_robots] =>
[is_favicon] =>
[is_posts_page] =>
[is_post_type_archive] =>
[query_vars_hash:WP_Query:private] => 16063b09e837c8b0771cc02d758ec1bd
[query_vars_changed:WP_Query:private] =>
[thumbnails_cached] =>
[allow_query_attachment_by_filename:protected] =>
[stopwords:WP_Query:private] =>
[compat_fields:WP_Query:private] => Array
(
[0] => query_vars_hash
[1] => query_vars_changed
)
[compat_methods:WP_Query:private] => Array
(
[0] => init_query_flags
[1] => parse_tax_query
)
)