ILSI Europe disseminates science by publishing articles on original research, literature reviews and gap analyses, and meeting proceedings in peer-reviewed journals with high impact factors. ILSI Europe also publishes books, monographs, white papers, and other reports.
Discover below our latest scientific publications.
Publication Date
Newest to Oldest
Small intestine vs. colon ecology and physiology: Why it matters in probiotic administration
Cell Reports Medicine, 2023
- ILSI Europe
We provide a detailed review unfolding how the physiological and anatomical differences between the small and large intestine affect gut microbiota composition, function, and plasticity. This information is key to understanding how gut microbiota manipulation, including probiotic administration, may strain-dependently transform host-microbe interactions at defined locations.
An Overview of Approaches for Analysing NIAS from different FCMs
ILSI Europe Report Series , 2023
- ILSI Europe
This overview gives an excellent introduction to analysing NIAS. It considers non-harmonised FCMs, highlighting various FCMs and their unique requirements for analysis of migrants (IAS (Intentionally Added Substances) or NIAS). It presents background information on different test conditions for the different FCMs and why the standard tests used for plastics outlined in the Commission Regulation (EU) No 10/2011 (14 January 2011 on plastic materials and articles intended to come into contact with food) are inappropriate in some instances for many non-harmonised FCMs.
Impacts of the Ukraine–Russia Conflict on the Global Food Supply Chain and Building Future Resilience
EuroChoices, 2023
- ILSI Europe
The immediate concerns and potential solutions to the global impacts of the Ukraine–Russia conflict were recently discussed by a panel of industry, academic and civil society experts convened by the European branch of the International Life Sciences Institute, all of whom are authors of this manuscript.
Health relevance of lowering postprandial glycaemia in the paediatric population through diet’: results from a multistakeholder workshop
European Journal of Nutrition , 2022
- ILSI Europe
To summarize current knowledge and gaps regarding the role of postprandial glycaemic response in the paediatric population, a workshop was organized in June 2021 by the European branch of the International Life Science Institute (ILSI). The workshop led to the consensus on the crucial role on health of postprandial glycaemic response in paediatric population.
A systematic review of breast milk microbiota composition and the evidence for transfer to and colonisation of the infant gut
Beneficial Microbes, 2022
- ILSI Europe
he intestinal microbiota plays a major role in infant health and development. However, the role of the breastmilk microbiota in infant gut colonisation remains unclear. A systematic review was performed to evaluate the composition of the breastmilk microbiota and evidence for transfer to/colonisation of the infant gut
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Research on gut microbiota has generally focused on fecal samples, representing luminal content of the large intestine. However, nutrient uptake is restricted to the small intestine. Abundant immune cell populations at this anatomical site combined with diminished mucus secretion and looser junctions (partly to allow for more efficient fluid and nutrient absorption) also results in intimate host-microbe interactions despite more rapid transit. It is thus crucial to dissect key differences in both ecology and physiology between small and large intestine to better leverage the immense potential of human gut microbiota imprinting, including probiotic engraftment at biological sensible niches. Here, we provide a detailed review unfolding how the physiological and anatomical differences between the small and large intestine affect gut microbiota composition, function, and plasticity. This information is key to understanding how gut microbiota manipulation, including probiotic administration, may strain-dependently transform host-microbe interactions at defined locations.
This review focusses its narrative on the intimate relationship between the host and its bacterial constituents of the small and large intestine.
Dowload the full paper
or click on the images below to download the EG one-pager summary and graphical abstract
Commissioned by the Probiotics Task Force
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The intestinal microbiota plays a major role in infant health and development. However, the role of the breastmilk microbiota in infant gut colonisation remains unclear. A systematic review was performed to evaluate the composition of the breastmilk microbiota and evidence for transfer to/colonisation of the infant gut. Searches were performed using PUBMED, OVID, LILACS and PROQUEST from inception until 18th March 2020 with a PUBMED update to December 2021. 88 full texts were evaluated before final critique based on study power, sample contamination avoidance, storage, purification process, DNA extraction/analysis, and consideration of maternal health and other potential confounders. Risk of skin contamination was reduced mainly by breast cleaning and rejecting the first milk drops. Sample storage, DNA extraction and bioinformatics varied. Several studies stored samples under conditions that may selectively impact bacterial DNA preservation, others used preculture reducing reliability. Only 15 studies, with acceptable sample size, handling, extraction, and bacterial analysis, considered transfer of bacteria to the infant. Three reported bacterial transfer from infant to breastmilk. Despite consistent evidence for the breastmilk microbiota, and recent studies using improved methods to investigate factors affecting its composition, few studies adequately considered transfer to the infant gut providing very little evidence for effective impact on gut colonisation.
Keywords
Expand
Microbiota, infant, breast milk, gut colonisation, systematic review
To download this open-access article, please click here.
Commissioned by the Early Nutrition and Long-Term Health Task Force.
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This review focusses its narrative on the intimate relationship between the host and its bacterial constituents of the small and large intestine.
Dowload the full paper
or click on the images below to download the EG one-pager summary and graphical abstract
Commissioned by the Probiotics Task Force
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