34th Annual European Meeting of the Toxicology Forum

Brussels, Belgium
22/10/2013 – 24/10/2013

The session, organised by ILSI Europe, presented the GUIDEA database, a centralised and comprehensive platform to assess the exposure of individuals to substances in foods and by promoting the use of Benchmark Dose Modelling (BDM) to derive a Margin of Exposure (MoE) for substances that are genotoxic and carcinogenic. Criteria to assess the impact of control measures on exposure and health was also tackled. Additionally, strategies to address exposure to multiple chemicals and to Non-Intentionally Added Substances were presented.

The session was supported by the following task forces: Food Intake Methodology, Risk Assessment of Genotoxic Carcinogens, Process Related Compounds and Natural Toxins, Threshold of Toxicological Concern and Packaging Materials.

SESSION III: Exposure Assessment

Guidance for Dietary Intake
Ben Smith, Firmenich, CH

Selection of Appropriate Tumour Data Sets for Benchmark Dose Modelling (BMD) and Derivation of a Margin of Exposure (MoE) for Substances That Are Genotoxic and Carcinogenic
Alan Boobis, Imperial College, UK

Criteria to Determine the Effectiveness of Dietary Exposure Reduction Measures on Human Health
Cian O' Mahony, Cremeglobal, IE

Assessing Mixtures Using TTC When Chemical Specific Data are Lacking
Heli Hollnagel, DOW Europe, CH

Analytical Strategy to Evaluate the Safety of FCM with a Focus on NIAS
Sander Koster, TNO, NL


The complete programme is available here.