GLUCOTYPES

Glucose variability patterns for precision nutrition in diabetes

Funding programme: EIC Pathfinder Challenge
Total budget: € 3 988 206
Consortium: 6 partners

Kobenhavns Universitet - Weizmann Institute Of Science - Universiteit Maastricht - Universidad De Santiago De Compostela - Academisch Ziekenhuis Leiden - International Life Sciences Institute Europe

Countries: 5

Denmark, Israel, Netherlands, Spain, Belgium.

Start: 1 October 2024 - End: 30 September 2028

Background

Type 2 diabetes (T2D) has emerged as a global epidemic, impacting 1 in 10 people worldwide and causing over 114,000 deaths annually in Europe. Despite extensive research, understanding the pathogenic mechanisms driving distinct disease subtypes and how diet influences glucose homeostasis has remained elusive. This knowledge gap leaves individuals with or at high risk of T2D without effective prevention or control strategies, urging a paradigm shift in our approach.

Objectives and expected impact

The GLUCOTYPES project brings together leading experts in nutrition, metabolic diseases, glycobiology, gut microbiome, epidemiology, and machine learning from five European countries to tackle this challenge.

The project capitalises on advancements in wearable technologies, molecular biology, and bioinformatics. It proposes to leverage hightemporal continuous glucose monitoring data to identify patterns of early glycaemic alterations, our “glucotypes”, a concept which forms the core hypothesis of this research program.

The objective is to advance the understanding of the divergent mechanisms that influence early glycaemic alterations and how specific diets could ameliorate these alterations. The project will establish a foundational yet comprehensive scientific groundwork to inform future precision diabetes nutrition strategies to prevent and improve the lives of all people affected by the disease.

Role of ILSI Europe

ILSI Europe is leading the preparation, implementation and oversight of the Communication, Dissemination and Exploitation strategy and activities. We will also facilitate and enable access to industry partners to support future valorisation of the project outcomes.

For more information, contact Ching-Yu Chang at: cchang@ilsieurope.be or Emilie Weynants at eweynants@ilsieurope.be